Backed by Science, Not Hype

At Thryv Nootryx, we believe in transparency and scientific integrity. Every ingredient in our nootropic formula is meticulously researched and backed by peer-reviewed, open-access studies from reputable journals. No gimmicks, no baseless claims—just real evidence supporting the cognitive-enhancing, memory-boosting, and neuroprotective effects of our carefully selected ingredients. Below, you’ll find links to independent research studies that validate the effectiveness of each compound, ensuring that our formulation is rooted in science, data, and proven results. Because when it comes to brain health, we rely on facts—not fads.

Lion’s Mane Mushroom Extract (Hericium erinaceus)

The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress, and Mood in Young Adults

Authors: S. Docherty, F. L. Doughty, E. F. Smith
Published in: Nutrients, 2023

Summary: This study examined the effects of Lion’s Mane mushroom supplementation on cognition and stress in young adults. The results indicated improved memory and reduced mental fatigue over time.

Exploring the Cognitive and Other Unique Health Benefits of Lion’s Mane Mushroom: A Systematic Review

Authors: S.I. Opanuga, M. F. Hossain
Published in: Natural Medicine, 2024

Summary: This systematic review highlights the cognitive benefits of Hericium erinaceus, emphasizing its potential for neuroprotection and memory improvement.

Acute Effects of a Standardised Extract of Hericium erinaceus (Lion’s Mane Mushroom) on Cognition and Mood in Healthy Younger Adults

Authors: S. G. Surendran, M. Heinrich, S. Surendran
Published in: Frontiers in Nutrition, 2025

Summary: This study confirmed that a standardized extract of Lion’s Mane significantly improved cognitive function and mood in young adults.

Bacopa Monnieri Extract

Meta-Analysis of Randomized Controlled Trials on Cognitive Effects of Bacopa Monnieri Extract

Authors: S. C. Kongkeaw, P. Dilokthornsakul
Published in: Journal of Ethnopharmacology, 2014

Summary: This meta-analysis confirmed the cognitive-enhancing effects of Bacopa Monnieri, especially in memory retention and recall.

The Cognitive-Enhancing Effects of Bacopa Monnieri: A Systematic Review of Randomized, Controlled Human Clinical Trials

Authors: S. M. P. Pase, J. Kean, J. Sarris
Published in: Journal of Alternative and Complementary Medicine, 2012

Summary: The review highlights Bacopa’s role in cognitive enhancement and neuroprotection, particularly in Alzheimer’s disease models.

Cognitive Enhancement and Neuroprotective Effects of Bacopa Monnieri in Alzheimer’s Disease Model

Authors: N. Uabundit, J. Wattanathorn, S. Mucimapura
Published in: Journal of Ethnopharmacology, 2010

Summary: Research indicates that Bacopa Monnieri exerts neuroprotective effects and helps in cognitive decline.

CDP-Choline (Citicoline)

Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Authors: E. Nakazaki, E. Mah, K. Sanoshy, D. Citrolo
Published in: The Journal of Nutrition, 2021

Summary: TCiticoline supplementation was associated with better cognitive performance and memory improvement in older adults.

Cytidinediphosphocholine (CDP‐Choline) for Cognitive and Behavioural Disturbances in the Elderly

Authors: M. Fioravanti, M. Yanagi
Published in: The Journal of Nutrition, 2021

Summary: Citicoline supplementation was associated with better cognitive performance and memory improvement in older adults. 

Cytidinediphosphocholine (CDP‐Choline) for Cognitive and Behavioural Disturbances in the Elderly

Authors: M. Fioravanti, M. Yanagi
Published in: The Journal of Nutrition, 2021

Summary: This systematic review found that Citicoline (CDP-Choline) helped in the improvement of cognitive functions in elderly individuals with chronic cerebral disorders.

‘Citicoline’ and Support of Memory Function: Evaluation of a Health Claim

Published in: European Food Safety Authority (EFSA), 2024

Summary: EFSA reviewed the evidence supporting Citicoline’s role in memory enhancement and brain function.

The Effect of Alpha-GPC and Huperzine-A on Short-Term Memory and Physical Performance

Authors: J.P. Isaacs
Published in: Eastern Kentucky University Thesis, 2019

Summary: Investigates the cognitive and physical benefits of combining Alpha-GPC with Huperzine-A.